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What is Systemic Lupus
Erythematosus (Lupus)?

Systemic lupus erythematosus (lupus) is a chronic autoimmune condition in which your immune system mistakenly attacks healthy tissues, causing inflammation and damage throughout the body. Lupus can affect the skin, joints, kidneys, heart, lungs, blood vessels, and brain, leading to a wide range of symptoms. Its course often alternates between flare-ups and periods of remission. With early diagnosis and expert treatment plans, lupus can be managed to reduce flares, preserve function, and protect long-term health.

Common Signs & Symptoms of Systemic Lupus
Erythematosus (Lupus):

  • Persistent fatigue and low energy
  • Joint pain, stiffness, and swelling
  • Skin rashes, including the classic butterfly-shaped rash across the cheeks and nose
  • Sensitivity to sunlight (photosensitivity)
  • Fever without an obvious cause
  • Swelling in the legs or around the eyes (possible kidney involvement)
  • Chest pain or shortness of breath
  • Mouth or nose ulcers
  • Hair thinning or hair loss
  • Cognitive difficulties or memory problems

Systemic Lupus Erythematosus (Lupus) Diagnosis & Treatment
at Cohen Medical Centers

During your initial consultation, your provider at Cohen Medical Centers, led by Dr. Cohen, will take a detailed medical history, review your symptoms, and conduct a thorough physical exam. We may order advanced blood tests to check for specific antibodies, assess organ function, and identify inflammation markers. Imaging or biopsies may be recommended to evaluate organ involvement. Based on these findings, we create a personalized treatment plan that addresses your disease pattern, symptom severity, and long-term health goals.

We offer a range of advanced therapies for lupus, including:

  • RITUXAN infusions to reduce immune system overactivity and control flares
  • BENLYSTA infusions to lower lupus activity and reduce steroid dependence
  • SAPHNELO infusions to target inflammation in moderate-to-severe lupus
  • Methylprednisolone infusions to quickly calm severe flare-ups and organ inflammation
  • IVIG therapy to regulate the immune response in resistant cases
  • Targeted oral or injectable medications to maintain remission and prevent flare-ups
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Systemic Lupus Erythematosus (Lupus) FAQs

What Causes Lupus?

The exact cause of lupus isn’t fully understood, but it’s believed to result from a combination of genetic, hormonal, and environmental factors. Your immune system becomes overactive and attacks healthy tissues. Certain triggers, such as infections, stress, or sun exposure, can spark flare-ups. Women are more commonly affected by lupus.

Is Lupus a Curable Disease?

Currently, lupus has no cure, but with early diagnosis and proper treatment, you can lead a full, active life. Modern therapies help control inflammation, prevent organ damage, and minimize the frequency of flare-ups. At Cohen Medical Centers, we aim to keep your disease activity as low as possible while protecting long-term health.

How is Lupus Diagnosed?

Lupus is diagnosed through a combination of symptom review, physical examination, lab testing for specific autoantibodies (such as ANA, anti-dsDNA, or anti-Smith), and sometimes imaging or biopsies. Because lupus symptoms can mimic other conditions, your provider takes time to rule out other causes before confirming a diagnosis.

What Can Trigger a Lupus Flare?

Common triggers include prolonged sun exposure, certain medications, infections, high stress levels, lack of sleep, and abrupt changes in treatment. Recognizing your triggers and working closely with your provider to avoid them can help you prevent or minimize flare-ups.

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Why Choose Cohen Medical Centers for Lupus Management?

Cohen Medical Centers is a leading destination for advanced lupus care, combining cutting-edge infusion therapies with compassionate, physician-led oversight. Led by Dr. Shariar Cohen, our dual-board-certified specialist in rheumatology, our team provides evidence-based treatments tailored to your unique conditions. From rapid flare control to long-term disease management, every protocol is customized for safety and lasting results. Schedule your consultation for lupus management at Cohen Medical Centers today.

Contact Our
Office Today

CONTACT US(805) 449-8781
Contact Us 805.449.8781